Robert M. Glaeser

Lawrence Berkeley National Laboratory

Election Year: 2016
Primary Section: 29, Biophysics and Computational Biology
Membership Type: Emeritus


Bob Glaeser is a biophysicist and structural biologist who grew up in Wisconsin, where he obtained a batchelor’s degree from the University of Wisconsin, Madison. After completing the PhD in Biophysics at the University of California, Berkeley, he spent one year as a post-doc in Oxford and a second year as a post-doc at the University of Chicago. He then returned to Berkeley as a faculty member and as a Staff Scientist at the Lawrence Berkeley National Laboratory. His University service includes a 5-year term as Divisional Dean of Biological Sciences, and his professional service includes a term as president of the Microscopy Society of America and a term as council member of the Biophysical Society. His professional honors include a Guggenheim Foundation Fellowship, the Alexander von Humboldt Award, membership in the American Academy of Arts and Sciences, and membership in the National Academy of Sciences.

Research Interests

Bob Glaeser’s research interests involve a mixture of (1) development of methodology for structural biology, with a major emphasis on electron microscopy, and (2) applications of this methodology to specific, biological projects. Areas of previous work have included: establishing the extent to which radiation damage limits imaging at high resolution, and the need to use averaging of noisy images to overcome those limitations; the use of frozen-hydrated specimens to preserve native, hydrated structure and, to a small extent, to improve the degree to which biological macromolecules can tolerate radiation damage; characterization of the resolution-limiting phenomenon of beam-induced movement; development of software tools for automated particle boxing and other aspects of high-throughput single-particle cryo-EM; and development of devices for in-focus phase contrast in transmission electron microscopy.

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